Identification of Timeliness of Anti-Tuberculosis Drug Intake and Pulmonary Tuberculosis Cure Rate at An-Nisa Hospital
Keywords:
Anti-tuberculosis; Cure Rate; Timeliness; Respiratory Tract; Tuberculosis
Abstract
Tuberculosis (TB) is the third leading cause of death across all age groups in Indonesia, as well as the leading cause of death from infectious diseases, with treatment success highly dependent on patient adherence, particularly the timeliness of anti-tuberculosis drug intake. This study aims to identify the relationship between medication timing adherence and the level of recovery among pulmonary TB patients at An-Nisa Hospital. This study employed a quantitative method with a cross-sectional approach. The study population consisted of tuberculosis patients who had undergone treatment at An-Nisa Hospital for six months. A total of 108 respondents were selected using an accidental sampling technique. The study was conducted in August 2025 over a period of two weeks at An-Nisa Hospital. Data were collected using a questionnaire. Data analysis using Spearman rank test. The findings demonstrated a statistically significant and moderate positive relationship between the timeliness of anti-tuberculosis drug intake and the pulmonary tuberculosis cure rate at An-Nisa Hospital (p = 0.000; r = 0.490). This study found a statistically significant and moderate positive relationship between the timeliness of anti-tuberculosis drug intake and the cure rate of pulmonary tuberculosis at An-Nisa Hospital.
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Clara Aulia Rachmah, Adi Dwi Susanto, & Imas Sartika. (2023b). Hubungan Tingkat Pengetahuan Dan Motivasi Dengan Kepatuhan Minum Obat Anti Tuberkulosis Pada Penderita TB Paru Di Rumah Sakit An-Nisa Tangerang. Jurnal Dunia Ilmu Kesehatan (JURDIKES), 1(2), 38–44. https://doi.org/10.59435/jurdikes.v1i2.149
Elisabeth, S., Septriani, I., & Derang, I. (2025). Hubungan Self Efficacy Dengan Kepatuhan Minum Obat Pada Pasien TB. British Medical Journal, 2(5474), 1333–1336.
Ferreira, I. B. B., Menezes, R. C., Araújo-Pereira, M., Rolla, V. C., Kritski, A. L., Cordeiro-Santos, M., Sterling, T. R., Staats, C., Amorim, G., Trajman, A., & Andrade, B. B. (2025). Effects of missed anti-tuberculosis therapy doses on treatment outcome: a multi-center cohort study. The Lancet Regional Health - Americas, 48, 1–10. https://doi.org/10.1016/j.lana.2025.101162
Ginting, A., Pakpahan, R., & Zebua, S. (2024). Gambaran Kepatuhan Minum Obat Penderita Tuberkulosis Paru Di Rumah Sakit Khusus Paru Medan Sumatera Utara. Innovative: Journal Of Social Science Research, 4(5), 7819–7834.
Husna, M., & Irawan, D. (2024). Faktor-Faktor Yang Mempengaruhi Kepatuhan Minum Obat Anti Tuberkulosis Pada Pasien Tuberkulosis Paru di RSUD Muda Sedia Aceh Tamiang. Public Health Journal, 1(3), 2024.
Irianti, T., & Mada, U. G. (2018). Anti-Tuberkulosis i | Buku Anti-tuberkulosis. (November).
Kemenkes. (2025). Gerakan Indonesia Akhiri TBC. https://kemkes.go.id/id/indonesias-movement-to-end-tb?utm_source=chatgpt.com
Kemenkes, P. (2020). Temukan TB Obati Sampai Sembuh Penatalaksanaan Tuberkulosis Resisten Obat di Indonesia.
Khoerunisa, E. F., Setiawan, A., Tarjuman, T., & Fathudin, Y. (2023). Lama Pengobatan terhadap Tingkat Kecemasan Pasien TB Paru di Poli Paru RSUD Al - Ihsan Provinsi Jawa Barat. Jurnal Keperawatan Indonesia Florence Nightingale, 3(1), 44–51. https://doi.org/10.34011/jkifn.v3i1.1362
Kigozi, G., Heunis, C., Chikobvu, P., Botha, S., & van Rensburg, D. (2017). Factors influencing treatment default among tuberculosis patients in a high burden province of South Africa. International Journal of Infectious Diseases, 54, 95–102. https://doi.org/10.1016/j.ijid.2016.11.407
Kurniasih, E & Daris, H. (2017). Tuberculosis-Mengenali Penyebab, Cara Penularan, dan Penanggulangan. 1–172.
Millata Hanifa, & Nurul Mutmainah. (2022a). Pengaruh Pemberian Edukasi Obat Terhadap Tingkat Kepatuhan Minum Obat Pada Pasien Tuberkulosis Paru Di Balai Besar Kesehatan Paru Masyarakat Surakarta Tahun 2019. Journal Of Pharmacy, 1(1), 111–122.
Millata Hanifa, & Nurul Mutmainah. (2022b). Pengaruh Pemberian Edukasi Obat Terhadap Tingkat Kepatuhan Minum Obat Pada Pasien Tuberkulosis Paru Di Balai Besar Kesehatan Paru Masyarakat Surakarta Tahun 2019. Journal Of Pharmacy, 1(1), 111–122.
Nisa, R., Ariwati, V. D., Rizky, A., Haeriyah, S., Delpia, Y. V., Prastiwi, R. S., Darmayanti, P. A. R., Fitrianingsih, N., Arfan, I., & Diel, M. M. (2023). Metodologi Penelitian Kesehatan Teori dan Implementasi dalam Penelitan (1st ed.). Yayasan Aurora Marifatul Syifa.
Perhimpunan Dokter Paru Indonesia. (2021). Tuberkulosis Pedoman Diagnosis dan Penatalaksanaan di Indonesia. In Perhimpunan Dokter Paru Indonesia (Vol. 001, Number 2014).
POM, B. (n.d.). Informasi Produk Terapetik.
Pratama, R. A., Diniarti, F., & Handayani, T. S. (2022). Faktor-Faktor Yang Mempengaruhi Kepatuhan Minum Obat Pada Pasien TB Paru Kasus Baru Di RSUD Curup Tahun 2022 Article Information Article history : Keywords : PENDAHULUAN Tuberkulosis ( TBC ) masih menjadi masalah kesehatan secara global . Sepertiga dari p. 25–36.
Pratiwi, D. D., & Syafina, I. (2025). Tingkat Kepatuhan Minum Obat Anti Tuberkulosis (OAT) Berhubungan Terhadap Kesembuhan Pasien Tuberkulosis Paru Di Rumah Sakit Umum Daerah Rokan Hulu. Jurnal Pandu Husada, 6(3), 11–20.
Puchalski Ritchie, L. M., van Lettow, M., Makwakwa, A., Kip, E. C., Straus, S. E., Kawonga, H., Hamid, J. S., Lebovic, G., Thorpe, K. E., Zwarenstein, M., Schull, M. J., Chan, A. K., Martiniuk, A., & van Schoor, V. (2020). Impact of a tuberculosis treatment adherence intervention versus usual care on treatment completion rates: results of a pragmatic cluster randomized controlled trial. Implementation Science, 15(1), 1–15. https://doi.org/10.1186/s13012-020-01067-y
Putra, A. D. (2024). Pengaruh Edukasi Penggunaan Aplikasi Tobat (Tekun Minum Obat) Terhadap Kepatuhan Minum Obat dan Kualitas Hidup Pasien TB Paru di Rumkit Tk. II Prof. dr. J.A. Latumeten. Jurnal Abdi Mahosada, 2(1), 70–79. https://doi.org/10.54107/abdimahosada.v2i1.374
RI, K. (2017). Tata Laksana Tuberkulosis. Jurnal Sains Dan Seni ITS, 6(1), 51–66.
Tasyakurillah, N. (2023). Dukungan Keluarga terhadap Kepatuhan Pengobatan Pasien TBC : Systematic Literature Review. HIGEIA (Journal of Public Health Research and Development), 7(Sup). https://doi.org/10.15294/HIGEIA.V7ISUP.65161
Wadah Kemitraan Penanggulangan Tuberkulosis. (2022). Aksi proteksi program terpadu kemitraan penanggulangan TBC. 1–23.
WHO. (2025a). Care and support interventions to enable TB treatment adherence | TB Knowledge Sharing. https://tbksp.who.int/en/node/3045?utm_source
WHO. (2025b). Strengthening TB surveillance to accelerate Indonesia’s path to Elimination. https://www.who.int/indonesia/news/detail/01-07-2025-strengthening-tb-surveillance-to-accelerate-indonesia-s-path-to-elimination?utm_source
WHO. (2026). Indonesia Charts Next Phase of TB Response through National Programme Review. https://www.who.int/indonesia/news/detail/08-01-2026-indonesia-charts-next-phase-of-tb-response-through-national-programme-review?utm.
Published
2026-06-30
Section
Articles
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