Application of P6 Acupressure on Children with Acute Lymphoblastic Leukemia Experiencing Post-Chemotherapy Nausea and Vomiting
Keywords:
Acupressure, Nausea, Vomiting, Chemotherapy, ALL
Abstract
Cancer refers to a condition where cells grow uncontrollably, potentially harming nearby healthy tissues and spreading via the lymphatic system and bloodstream. Among various types of leukemia, Acute Lymphoblastic Leukemia (ALL) is the most frequently found in pediatric patients. Chemotherapy, the primary treatment, often causes nausea and vomiting, affecting the child's comfort and nutritional intake. This study aimed to evaluate the effectiveness of P6 acupressure therapy in reducing nausea and vomiting in children with ALL. A case study was conducted involving two children undergoing chemotherapy at unit Anggrek, RS X, Jakarta. P6 acupressure was applied for 3–4 consecutive days. Results indicated a significant decrease in nausea intensity and vomiting frequency in one patient, while the other showed a mild reduction. The findings demonstrate that P6 acupressure is an effective, non-pharmacological nursing intervention for managing chemotherapy-induced nausea and vomiting in pediatric patients. This therapy can be safely taught to caregivers as part of home-based supportive care, providing practical implications for nursing practice in pediatric oncology settings.
References
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Bahrami, T., Rejeh, N., Heravi-Karimooi, M., Montazeri, A., & Sharif Nia, H. (2020). Effect of acupressure on anxiety: A meta-analysis. Journal of Acupuncture and Meridian Studies, 13(1), 12–21. https://doi.org/10.1016/j.jams.2019.10.002
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Farhad, H. M., Rahmani, M., & Hamid, A. (2016). Effectiveness of acupressure in reducing chemotherapy-induced nausea and vomiting. International Journal of Advanced Nursing Studies, 5(2), 95–100. https://doi.org/10.14419/ijans.v5i2.6489
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Gustini, M. D., Suwondo, A., & Haryani, D. (2019). The effectiveness of a combination of antiemetics and acupressure in reducing nausea and vomiting in cancer patients. Jurnal Keperawatan Soedirman, 14(3), 123–130.
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Lydia, F. (2019). Pengaruh terapi akupresur terhadap mual muntah pada anak yang menjalani kemoterapi di Rumah Sakit Kanker Dharmais Jakarta. Jurnal Keperawatan Anak, 7(1), 55–62.
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Ristika, R. (2019). Manajemen terintegrasi pada anak dengan leukemia limfoblastik akut. Yogyakarta: Nuha Medika.
Rosiana, D., Mahardika, W. A., & Rahmawati, A. (2022). Pengaruh terapi bermain terhadap tingkat kecemasan anak usia prasekolah yang mengalami hospitalisasi di RSUD Wonosari. Jurnal Kesehatan Kusuma Husada, 13(2), 173–180. https://jurnal.umkus.ac.id/index.php/kusuka/article/view/1033
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Wang, H., Li, Y., & Zhang, Y. (2021). Acupressure for chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis. Complementary Therapies in Clinical Practice, 43, 101341. https://doi.org/10.1016/j.ctcp.2021.101341
Yuliar, T. P., Susanah, S., & Nurhidayah, I. (2019). Effect of Nei Guan Acupressure Point as Adjuvant Therapy on Highly Emetogenic Chemotherapy-Induced Nausea-Vomiting in School-Age Children with Cancer. Jurnal Keperawatan Padjadjaran, 7(1), 67–77. https://doi.org/10.24198/jkp.v7i1.657
Zhong, W., Shahbaz, O., Teskey, G., Beever, A., Kachour, N., Venketaraman, V., & Darmani, N. A. (2021). Mechanisms of nausea and vomiting: Current knowledge and recent advances in intracellular emetic signaling systems. International Journal of Molecular Sciences, 22(11). https://doi.org/10.3390/ijms22115797
Amba Bunga, S., & Siswadi, Y. (2024). Efektivitas Akupresur terhadap Penurunan Mual Muntah Pasien Kemoterapi: Literature Review. Media Publikasi Promosi Kesehatan Indonesia (MPPKI), 7(4), 852–863. https://doi.org/10.56338/mppki.v7i4.5104
Ayers, S., & Olowe, P. (2015). Complementary therapy use in pediatric oncology. Pediatric Blood & Cancer, 62(10), 1740–1745. https://doi.org/10.1002/pbc.25538
Bahrami, T., Rejeh, N., Heravi-Karimooi, M., Montazeri, A., & Sharif Nia, H. (2020). Effect of acupressure on anxiety: A meta-analysis. Journal of Acupuncture and Meridian Studies, 13(1), 12–21. https://doi.org/10.1016/j.jams.2019.10.002
Elisafitri, E., Wahyuni, S., & Fitriyani, P. (2019). Acute lymphoblastic leukemia in children. Jurnal Kesehatan Anak, 7(1), 1–7.
Farhad, H. M., Rahmani, M., & Hamid, A. (2016). Effectiveness of acupressure in reducing chemotherapy-induced nausea and vomiting. International Journal of Advanced Nursing Studies, 5(2), 95–100. https://doi.org/10.14419/ijans.v5i2.6489
Fatikasari, A. C., Ayu, W. D., & Masruhim, M. A. (2018). Kajian Penggunaan Obat Kemoterapi Pada Pasien Leukimia Anak Di RSUD Abdul Wahab Sjahranie Kota Samarinda. Angewandte Chemie International Edition, 6(11), 951–952., November, 269–277.
Gustini, M. D., Suwondo, A., & Haryani, D. (2019). The effectiveness of a combination of antiemetics and acupressure in reducing nausea and vomiting in cancer patients. Jurnal Keperawatan Soedirman, 14(3), 123–130.
Hasyimzoem, A. (2018). Patofisiologi leukemia limfoblastik akut. Jakarta: Media Ilmu.
Lydia, F. (2019). Pengaruh terapi akupresur terhadap mual muntah pada anak yang menjalani kemoterapi di Rumah Sakit Kanker Dharmais Jakarta. Jurnal Keperawatan Anak, 7(1), 55–62.
Rahmah, N., & Alfiyanti, D. (2021). Reduction of nausea and vomiting in acute lymphoblastic leukemia patients undergoing chemotherapy with acupressure therapy at point P6 (Neiguan) and point ST35 (Zusanli). Jurnal Keperawatan Anak, 6(2), 45–51.
Ristika, R. (2019). Manajemen terintegrasi pada anak dengan leukemia limfoblastik akut. Yogyakarta: Nuha Medika.
Rosiana, D., Mahardika, W. A., & Rahmawati, A. (2022). Pengaruh terapi bermain terhadap tingkat kecemasan anak usia prasekolah yang mengalami hospitalisasi di RSUD Wonosari. Jurnal Kesehatan Kusuma Husada, 13(2), 173–180. https://jurnal.umkus.ac.id/index.php/kusuka/article/view/1033
Rukayah, R., Prihatini, E., & Vetabilivy, V. (2018). The effectiveness of acupressure therapy on the intensity of nausea and vomiting in children undergoing chemotherapy. Jurnal Ilmu dan Teknologi Kesehatan, 8(2), 101–108.
Sitorus, Y. M. (2020). Efektivitas terapi bermain terhadap tingkat kecemasan anak yang dirawat di ruang rawat inap RSUD Arifin Achmad Pekanbaru. Jurnal Endurance: Kajian Ilmiah Problema Kesehatan, 5(2), 350–356. https://doi.org/10.22216/jen.v5i2.4722
Soliman, G. H., Alagizy, H., & Shehata, O. S. M. H. (2021). Efficacy of Non Pharmacological Technique on Chemotherapy Induced Nausea , Vomiting and Retching among Breast Cancer Patients. Journal of Nursing and Health Science, 6(5), 60–72. https://doi.org/10.9790/1959-0605056072
Srinatania, D., & Revy Citra Carlina. (2023). Penatalaksanaan Akupresur Dalam Mengatasi Masalah Mual Dan Muntah Akibat Kemoterapi Pada Anak Dengan Kanker Di Ruang Perawatan Hematologi Onkologi Thalasemia Rumah Sakit Hermina Pasteur. Jurnal Ilmiah Keperawatan (Scientific Journal of Nursing), 9(3), 37–43. https://doi.org/10.33023/jikep.v9i3.1588
Utami, T. A., & Anggraeni, L. D. (2023). Korelasi Penghasilan Orang Tua terhadap Kualitas Hidup Anak yang Mengalami Talasemia Mayor. Faletehan Health Journal, 10(02), 148–158. https://doi.org/10.33746/fhj.v10i02.577
Wang, H., Li, Y., & Zhang, Y. (2021). Acupressure for chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis. Complementary Therapies in Clinical Practice, 43, 101341. https://doi.org/10.1016/j.ctcp.2021.101341
Yuliar, T. P., Susanah, S., & Nurhidayah, I. (2019). Effect of Nei Guan Acupressure Point as Adjuvant Therapy on Highly Emetogenic Chemotherapy-Induced Nausea-Vomiting in School-Age Children with Cancer. Jurnal Keperawatan Padjadjaran, 7(1), 67–77. https://doi.org/10.24198/jkp.v7i1.657
Zhong, W., Shahbaz, O., Teskey, G., Beever, A., Kachour, N., Venketaraman, V., & Darmani, N. A. (2021). Mechanisms of nausea and vomiting: Current knowledge and recent advances in intracellular emetic signaling systems. International Journal of Molecular Sciences, 22(11). https://doi.org/10.3390/ijms22115797
Published
2025-12-01
Section
Articles
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